The pre-registration of the Restructure trial is now open, you can find all the details at https://clinicaltrials.gov/study/NCT06113146 …
Recent advances in science suggest that the speed of eating has a large influence on the extent to which we feel full, which in turn determines how much we eat during a meal. But the exact relation between the texture of food, the speed of eating and how much we eat (energy intake) is not yet completely understood. "RESTRUCTURE: Developing and implementing innovative and evidence-based food design principles to moderate energy intake " will demonstrate some of the causal mechanisms by which these properties may be responsible for overeating. The project results will inform food design rules and tools to guide the development of foods that help limit food intake and prevent overweight and obesity.
Read moreThe objective of the RESTRUCTURE project is to develop evidence-based models based on food properties that
The research will be carried out in two stages:
The hypothesis will be tested by offering two different diets equal in calories (energy density) and liking (palatability) to participants:
By comparing how much food is eaten within each of the diets, the researchers will find out the relations between food processing, how fast the food is eaten, and how much food is eaten.
Eating rate, energy intake rate, energy density… telling them apart is not always self-evident. Click here for more on what’s behind these terms and the other key concepts related to food processing and the RESTRUCTURE study.
The speed of eating (measured in g/min and kcal/min. Studies show that eating slowly can reduce energy intake. Eating rate depends on macronutrient composition and food structure and processing.
The number of kcal (calories) per gram of food. There is sufficient evidence that higher energy densities lead to sustained increases in energy intake and weight gain. Energy density is generally higher in ultra-processed foods and a likely explanation for overconsumption, potentially in addition to texture related causes. RESTRUCTURE aims to control for this and keep energy density levels consistent across the diets, to investigate the influence of texture and eating rate.
The number of kcal (calories) ingested.
The speed at which calories are consumed (measured in kcal/min). This combines the energy density of a food with its eating rate. Energy density (kcal/g) x Eating rate (g/min) = Energy intake rate (kcal/min)
Foods that have a relatively high energy intake rate (the energy provided by foods or drinks is consumed quickly).
Foods that have a relatively low energy intake rate (the energy provided by foods or drinks is consumed slowly).
By shedding light on how the composition and texture-properties influence eating rate, RESTRUCTURE will produce the criteria to define “slow foods” and the principles that can be used to guide their development.
Food processing can be described as the methods used to turn fresh foods into food products, such as heating, drying, fermenting, extraction, extrusion, packaging.
In the context of the project, food reformulation is the re-designing of an existing food product with the objective of making it healthier. Currently reformulation typically focuses on reducing “risk nutrients” including saturated fat, trans fat, sugar, salt, and calories. RESTRUCTURE aims to integrate research findings on texture and eating rate into reformulation goals.
Food texture is defined as “all the mechanical, geometrical and surface attributes of a product perceptible by mechanical, tactile, or visual and auditory receptors” (International Standards Organization, ISO, 1994). Textures include ‘hardness’ or ‘softness’, ‘crunchiness’ or ‘crumbliness’, or 'viscosity'. Texture is multidimensional and dynamic in nature, as it changes during eating.
The NOVA classification seeks to categorise food products based on the extent and purpose of processing, into four groups:
Overweight and obesity are among the most urgent nutrition related problems in the world affecting more than 2 billion people. By helping to reduce energy intake rate of foods, RESTRUCTURE aims to contribute to prevention of overweight and obesity. Obesity is however a complex issue, requiring multiple interventions at different levels.
The degree to which a food is liked. Studies on the effect of eating rate/food processing need to account for the palatability of food. RESTRUCTURE aims to control for this and keep palatability levels consistent across the diets.
Satiation is defined as the processes which occur in the body during eating that lead us to finish eating/end a meal.
While definitions vary, ultra-processed foods are described as “formulations of ingredients, mostly of exclusive industrial use, that result from a series of industrial processes (hence ‘ultra-processed’).” The RESTRUCTURE trial will determine whether the effects of texture on energy intake rate are independent of being classified as ultra-processed foods.
The project’s main
research activities and research design are independently developed by
the research team.
The governance of the project is composed of the Steering Committee and the
Advisory Committee. The research team can only receive input and scientific
support from these bodies following specific modalities.